Research workbench
AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (Q8Z6F5)
Analyse AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (Q8Z6F5) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8Z6F5
- Type
- protein
- Length
- 649 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
- Molecule
- DNA topoisomerase 3
- UniProt
- Q8Z6F5
- Pockets
- 5 · best druggability 0.71
Structure
1 distinct chain · 45% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 3 | protein | 649 | 45% helix, 18% strand | Q8Z6F5 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1129 | 0.71 | 0.75 | 95 | empty |
| 2 | 305 | 0.63 | 0.80 | 39 | empty |
| 3 | 125 | 0.40 | 0.75 | 20 | empty |
| 4 | 53 | 0.34 | 0.77 | 14 | empty |
| 5 | 70 | 0.31 | 0.74 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8Z6F5
- Elsewhere: UniProt Q8Z6F5 · AlphaFold DB Q8Z6F5
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