Research workbench
AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (Q73E74)
Analyse AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (Q73E74) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q73E74
- Type
- protein
- Length
- 729 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3e0aC98Dc58EA794394EdeA1992f0D3Ca753d03c
- Molecule
- DNA topoisomerase 3
- UniProt
- Q73E74
- Pockets
- 10 · best druggability 0.77
Structure
1 distinct chain · 43% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 3 | protein | 729 | 43% helix, 21% strand | Q73E74 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 958 | 0.77 | 0.80 | 94 | empty |
| 2 | 781 | 0.71 | 0.77 | 55 | empty |
| 3 | 128 | 0.61 | 0.86 | 30 | empty |
| 4 | 223 | 0.54 | 0.78 | 26 | empty |
| 5 | 115 | 0.39 | 0.75 | 20 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q73E74
- Elsewhere: UniProt Q73E74 · AlphaFold DB Q73E74
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