Research workbench
AlphaFold monomer V2.0 prediction for DNA topoisomerase 1 (Q9X3X7)
Analyse AlphaFold monomer V2.0 prediction for DNA topoisomerase 1 (Q9X3X7) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9X3X7
- Type
- protein
- Length
- 1,212 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x81d3EC8733E3Df35c032988194E7E41e96b4Ea84
- Molecule
- DNA topoisomerase 1
- UniProt
- Q9X3X7
- Pockets
- 7 · best druggability 0.64
Structure
1 distinct chain · 27% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 1 | protein | 1212 | 27% helix, 16% strand | Q9X3X7 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 226 | 0.64 | 0.83 | 36 | empty |
| 2 | 529 | 0.62 | 0.75 | 45 | empty |
| 3 | 553 | 0.61 | 0.74 | 65 | empty |
| 4 | 254 | 0.56 | 0.78 | 38 | empty |
| 5 | 147 | 0.44 | 0.76 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X3X7
- Elsewhere: UniProt Q9X3X7 · AlphaFold DB Q9X3X7
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