Research workbench
AlphaFold monomer V2.0 prediction for DNA topoisomerase 1 (Q2YXL8)
Analyse AlphaFold monomer V2.0 prediction for DNA topoisomerase 1 (Q2YXL8) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q2YXL8
- Type
- protein
- Length
- 689 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x81957cf22C1850f268Ea6B427f0c14A4D40792f1
- Molecule
- DNA topoisomerase 1
- UniProt
- Q2YXL8
- Pockets
- 5 · best druggability 0.73
Structure
1 distinct chain · 36% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 1 | protein | 689 | 36% helix, 26% strand | Q2YXL8 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1001 | 0.73 | 0.77 | 94 | empty |
| 2 | 223 | 0.55 | 0.78 | 25 | empty |
| 3 | 138 | 0.42 | 0.75 | 17 | empty |
| 4 | 80 | 0.40 | 0.78 | 13 | empty |
| 5 | 115 | 0.37 | 0.73 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2YXL8
- Elsewhere: UniProt Q2YXL8 · AlphaFold DB Q2YXL8
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