Research workbench

AlphaFold monomer V2.0 prediction for DNA topoisomerase 1 (Q9YB01)

Analyse AlphaFold monomer V2.0 prediction for DNA topoisomerase 1 (Q9YB01) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q9YB01
Type: protein
Length: 673 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x75EB5691D610F6d3120681e3fAfC5D43543015dA
Molecule: DNA topoisomerase 1
UniProt: Q9YB01
Pockets: 7 · best druggability 0.67

Structure

1 distinct chain · 47% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA topoisomerase 1	protein	673	47% helix, 19% strand	Q9YB01

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	708	0.67	0.75	48	empty
2	220	0.59	0.80	31	empty
3	254	0.58	0.79	28	empty
4	160	0.45	0.76	21	empty
5	148	0.43	0.75	18	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9YB01
Elsewhere: UniProt Q9YB01 · AlphaFold DB Q9YB01

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