Research workbench
AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member 18 (Q9Y5U5)
Analyse AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9Y5U5
- Type
- protein
- Length
- 241 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
- Molecule
- Tumor necrosis factor receptor superfamily member 18
- UniProt
- Q9Y5U5
- Pockets
- 1 · best druggability 0.44
Structure
1 distinct chain · 25% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tumor necrosis factor receptor superfamily member 18 | protein | 241 | 25% helix, 18% strand | Q9Y5U5 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 164 | 0.44 | 0.75 | 32 | empty |
Modifications
Observed in the structure: 9 disulfide (disulfide).
Compared structures
- 7KHD · Human gitr-gitrl complex · an experimental structure of the same protein · chain A against C, TM-score 0.39
- 7KHD · Human GITR-GITRL complex · an experimental structure of the same protein · chain A against C, TM-score 0.39
- 7LAW · crystal structure of GITR complex with GITR-L · an experimental structure of the same protein · chain A against R, TM-score 0.38
- 7LAW · Crystal structure of gitr complex with gitr-L · an experimental structure of the same protein · chain A against R, TM-score 0.38
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y5U5
- Elsewhere: UniProt Q9Y5U5 · AlphaFold DB Q9Y5U5
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