Research workbench
AlphaFold monomer V2.0 prediction for transmembrane protease serine 12 (Q86WS5)
Analyse AlphaFold monomer V2.0 prediction for transmembrane protease serine 12 (Q86WS5) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q86WS5
- Type
- protein
- Length
- 348 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd91633319BDB0a92cbC4f08DeA734Bf74C030064
- Molecule
- Transmembrane protease serine 12
- UniProt
- Q86WS5
- Pockets
- 5 · best druggability 0.58
Structure
1 distinct chain · 20% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transmembrane protease serine 12 | protein | 348 | 20% helix, 27% strand | Q86WS5 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 97 | 0.58 | 0.86 | 25 | empty |
| 2 | 267 | 0.52 | 0.75 | 30 | empty |
| 3 | 109 | 0.43 | 0.77 | 21 | empty |
| 4 | 145 | 0.42 | 0.75 | 26 | empty |
| 5 | 50 | 0.30 | 0.77 | 14 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q86WS5
- Elsewhere: UniProt Q86WS5 · AlphaFold DB Q86WS5
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