Research workbench
AlphaFold monomer V2.0 prediction for transmembrane protease serine 3 (P57727)
Analyse AlphaFold monomer V2.0 prediction for transmembrane protease serine 3 (P57727) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P57727
- Type
- protein
- Length
- 454 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd302f04514ad817d3281793c7434A949dEEd5b52
- Molecule
- Transmembrane protease serine 3
- UniProt
- P57727
- Pockets
- 5 · best druggability 0.65
Structure
1 distinct chain · 19% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transmembrane protease serine 3 | protein | 454 | 19% helix, 27% strand | P57727 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 206 | 0.65 | 0.84 | 28 | empty |
| 2 | 100 | 0.47 | 0.81 | 21 | empty |
| 3 | 102 | 0.34 | 0.74 | 18 | empty |
| 4 | 52 | 0.32 | 0.77 | 16 | empty |
| 5 | 58 | 0.30 | 0.76 | 18 | empty |
Modifications
Observed in the structure: 10 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P57727
- Elsewhere: UniProt P57727 · AlphaFold DB P57727
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