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AlphaFold monomer V2.0 prediction for ENDOSOMAL/LYSOSOMAL potassium channel TMEM175 (Q6AY05)

Analyse AlphaFold monomer V2.0 prediction for ENDOSOMAL/LYSOSOMAL potassium channel… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q6AY05
Type
protein
Length
499 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB35df660264f41795De49C83276C108A4ba91ADE
Molecule
ENDOSOMAL/LYSOSOMAL potassium channel TMEM175
UniProt
Q6AY05
Pockets
5 · best druggability 0.83

Structure

1 distinct chain · 75% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AENDOSOMAL/LYSOSOMAL potassium channel TMEM175protein49975% helix, 2% strandQ6AY05

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12850.830.9451empty
21440.560.8220empty
31050.470.8019empty
4740.370.7719empty
5530.250.7314empty

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