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AlphaFold monomer V2.0 prediction for ENDOSOMAL/LYSOSOMAL potassium channel TMEM175 (Q32PG7)

Analyse AlphaFold monomer V2.0 prediction for ENDOSOMAL/LYSOSOMAL potassium channel… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q32PG7
Type
protein
Length
479 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x10CE6839fAB1d16e972AA2437070Dd76D75b7C48
Molecule
ENDOSOMAL/LYSOSOMAL potassium channel TMEM175
UniProt
Q32PG7
Pockets
5 · best druggability 0.80

Structure

1 distinct chain · 71% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AENDOSOMAL/LYSOSOMAL potassium channel TMEM175protein47971% helix, 2% strandQ32PG7

Pockets

5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17470.800.8362empty
2680.580.8922empty
32700.530.7543empty
42380.510.7623empty
51630.450.7529empty

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