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AlphaFold monomer V2.0 prediction for T-cell immunoglobulin and mucin domain-containing protein 4 (Q6U7R4)

Analyse AlphaFold monomer V2.0 prediction for T-cell immunoglobulin and mucin… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q6U7R4
Type
protein
Length
343 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xC8051e607417A2890274BC226Eb475379945EA5C
Molecule
T-cell immunoglobulin and mucin domain-containing protein 4
UniProt
Q6U7R4
Pockets
1 · best druggability 0.57

Structure

1 distinct chain · 20% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AT-cell immunoglobulin and mucin domain-containing protein 4protein34320% helix, 15% strandQ6U7R4

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13530.570.7637empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

  • 3BI9 · Tim-4 · an experimental structure of the same protein · chain A against X, TM-score 0.33
  • 3BI9 · TIM-4 · an experimental structure of the same protein · chain A against X, TM-score 0.33
  • 3BIA · Tim-4 in complex with sodium potassium tartrate · an experimental structure of the same protein · chain A against X, TM-score 0.32
  • 3BIA · Tim-4 in complex with sodium potassium tartrate · an experimental structure of the same protein · chain A against X, TM-score 0.32
  • 3BIB · Tim-4 in complex with phosphatidylserine · an experimental structure of the same protein · chain A against X, TM-score 0.32
  • 3BIB · Tim-4 in complex with phosphatidylserine · an experimental structure of the same protein · chain A against X, TM-score 0.32

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