Research workbench
AlphaFold monomer V2.0 prediction for hydroxyethylthiazole kinase (P39593)
Analyse AlphaFold monomer V2.0 prediction for hydroxyethylthiazole kinase (P39593) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P39593
- Type
- protein
- Length
- 272 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8523A13A5C4Df46E43111d04fcB533Ce2Ca950B4
- Molecule
- Hydroxyethylthiazole kinase
- UniProt
- P39593
- Pockets
- 3 · best druggability 0.47
Structure
1 distinct chain · 53% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hydroxyethylthiazole kinase | protein | 272 | 53% helix, 14% strand | P39593 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 183 | 0.47 | 0.75 | 26 | empty |
| 2 | 50 | 0.32 | 0.77 | 18 | empty |
| 3 | 78 | 0.30 | 0.72 | 19 | empty |
Compared structures
- 1ESJ · Crystal structure of thiazole kinase mutant (C198S) · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 1ESJ · Crystal structure of thiazole kinase mutant (C198S) · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 1C3Q · Crystal structure of native thiazole kinase in the monoclinic form · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 1C3Q · Crystal structure of native thiazole kinase in the monoclinic form · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 1EKK · Crystal structure of hydroxyethylthiazole kinase in the R3 form with hydroxyethylthiazole · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 1EKK · Crystal structure of hydroxyethylthiazole kinase in the R3 form with hydroxyethylthiazole · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 1ESQ · Crystal structure of thiazole kinase mutant (C198S) with ATP and thiazole phosphate. · an experimental structure of the same protein · chain A against C, TM-score 0.95
- 1ESQ · Crystal structure of thiazole kinase mutant (C198S) with ATP and thiazole phosphate. · an experimental structure of the same protein · chain A against C, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P39593
- Elsewhere: UniProt P39593 · AlphaFold DB P39593
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