Research workbench
AlphaFold monomer V2.0 prediction for thyroid hormone receptor alpha (O42450)
Analyse AlphaFold monomer V2.0 prediction for thyroid hormone receptor alpha (O42450) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O42450
- Type
- protein
- Length
- 402 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x54FBC17A5C73fF6f44d925D726c013269Fd7F733
- Molecule
- Thyroid hormone receptor alpha
- UniProt
- O42450
- Pockets
- 3 · best druggability 0.83
Structure
1 distinct chain · 56% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thyroid hormone receptor alpha | protein | 402 | 56% helix, 4% strand | O42450 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 179 | 0.83 | 0.98 | 32 | empty |
| 2 | 122 | 0.45 | 0.78 | 16 | empty |
| 3 | 111 | 0.42 | 0.77 | 20 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O42450
- Elsewhere: UniProt O42450 · AlphaFold DB O42450
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