Research workbench
AlphaFold monomer V2.0 prediction for thyroid hormone receptor alpha (P63058)
Analyse AlphaFold monomer V2.0 prediction for thyroid hormone receptor alpha (P63058) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P63058
- Type
- protein
- Length
- 492 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6BdE6afbf1E5F079b9F4169e9362dC26693b311A
- Molecule
- Thyroid hormone receptor alpha
- UniProt
- P63058
- Pockets
- 4 · best druggability 0.83
Structure
1 distinct chain · 45% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thyroid hormone receptor alpha | protein | 492 | 45% helix, 4% strand | P63058 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 187 | 0.83 | 0.97 | 31 | empty |
| 2 | 875 | 0.72 | 0.77 | 74 | empty |
| 3 | 251 | 0.58 | 0.78 | 25 | empty |
| 4 | 96 | 0.42 | 0.78 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63058
- Elsewhere: UniProt P63058 · AlphaFold DB P63058
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