Research workbench
AlphaFold monomer V2.0 prediction for thromboxane-a synthase (P47787)
Analyse AlphaFold monomer V2.0 prediction for thromboxane-a synthase (P47787) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P47787
- Type
- protein
- Length
- 534 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
- Molecule
- Thromboxane-a synthase
- UniProt
- P47787
- Pockets
- 6 · best druggability 0.84
Structure
1 distinct chain · 53% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thromboxane-a synthase | protein | 534 | 53% helix, 9% strand | P47787 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1163 | 0.84 | 0.85 | 90 | empty |
| 2 | 293 | 0.65 | 0.81 | 38 | empty |
| 3 | 174 | 0.54 | 0.79 | 25 | empty |
| 4 | 58 | 0.41 | 0.82 | 13 | empty |
| 5 | 91 | 0.40 | 0.78 | 16 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P47787
- Elsewhere: UniProt P47787 · AlphaFold DB P47787
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