Research workbench
AlphaFold monomer V2.0 prediction for TAF5-like RNA polymerase II P300/CBP-associated factor-associated factor 65 kda subunit 5L (O75529)
Analyse AlphaFold monomer V2.0 prediction for TAF5-like RNA polymerase II… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O75529
- Type
- protein
- Length
- 589 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf0Aa067888A3e900110FDD599F9Aa39D7DF7a484
- Molecule
- TAF5-like RNA polymerase II P300/CBP-associated factor- associated factor 65 kda subunit…
- UniProt
- O75529
- Pockets
- 4 · best druggability 0.77
Structure
1 distinct chain · 27% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | TAF5-like RNA polymerase II P300/CBP-associated factor- associated factor 65 kda subunit 5L | protein | 589 | 27% helix, 30% strand | O75529 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 777 | 0.77 | 0.81 | 54 | empty |
| 2 | 719 | 0.69 | 0.76 | 67 | empty |
| 3 | 206 | 0.53 | 0.77 | 25 | empty |
| 4 | 78 | 0.33 | 0.74 | 14 | empty |
Compared structures
- 7KTR · Cryo-EM structure of the human saga coactivator complex (trrap, core) · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 7KTR · Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core) · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 7KTS · Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing… · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 8H7G · Cryo-EM structure of the human SAGA complex · an experimental structure of the same protein · chain A against H, TM-score 0.52
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75529
- Elsewhere: UniProt O75529 · AlphaFold DB O75529
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