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AlphaFold monomer V2.0 prediction for tyrosine--tRNA ligase (A8AH18)

Analyse AlphaFold monomer V2.0 prediction for tyrosine--tRNA ligase (A8AH18) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
A8AH18
Type
protein
Length
428 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xF336F3B74E376B91b0149E66DCdF03429c696250
Molecule
Tyrosine--tRNA ligase
UniProt
A8AH18
Pockets
6 · best druggability 0.73

Structure

1 distinct chain · 52% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATyrosine--tRNA ligaseprotein42852% helix, 15% strandA8AH18

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14520.730.8350empty
21000.370.7415empty
3840.350.7517empty
4790.340.7512empty
5580.320.7713empty

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