Research workbench
AlphaFold monomer V2.0 prediction for tyrosine--tRNA ligase, mitochondrial (P12063)
Analyse AlphaFold monomer V2.0 prediction for tyrosine--tRNA ligase, mitochondrial… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P12063
- Type
- protein
- Length
- 669 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
- Molecule
- Tyrosine--tRNA ligase, mitochondrial
- UniProt
- P12063
- Pockets
- 11 · best druggability 0.77
Structure
1 distinct chain · 48% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine--tRNA ligase, mitochondrial | protein | 669 | 48% helix, 10% strand | P12063 |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 508 | 0.77 | 0.84 | 38 | empty |
| 2 | 455 | 0.73 | 0.83 | 48 | empty |
| 3 | 319 | 0.64 | 0.80 | 39 | empty |
| 4 | 568 | 0.62 | 0.74 | 52 | empty |
| 5 | 53 | 0.49 | 0.86 | 18 | empty |
Compared structures
- 4OJM · Crystal structure of a C-terminally truncated CYT-18 protein including N-terminal residues · an experimental structure of the same protein · chain A against X, TM-score 0.57
- 4OJM · Crystal structure of a C-terminally truncated cyt-18 protein including N-terminal residues · an experimental structure of the same protein · chain A against X, TM-score 0.57
- 1Y42 · Crystal structure of a C-terminally truncated CYT-18 protein · an experimental structure of the same protein · chain A against X, TM-score 0.55
- 1Y42 · Crystal structure of a C-terminally truncated cyt-18 protein · an experimental structure of the same protein · chain A against X, TM-score 0.55
- 2RKJ · Cocrystal structure of a tyrosyl-tRNA synthetase splicing factor with a group I intron RNA · an experimental structure of the same protein · chain A against A, TM-score 0.54
- 2RKJ · Cocrystal structure of a tyrosyl-tRNA synthetase splicing factor with a group I intron RNA · an experimental structure of the same protein · chain A against A, TM-score 0.54
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P12063
- Elsewhere: UniProt P12063 · AlphaFold DB P12063
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