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AlphaFold monomer V2.0 prediction for leucine--tRNA ligase (Q8DFE2)

Analyse AlphaFold monomer V2.0 prediction for leucine--tRNA ligase (Q8DFE2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q8DFE2
Type
protein
Length
857 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB05a6C07895e32B47A59E248baa07d66d77b0e17
Molecule
Leucine--tRNA ligase
UniProt
Q8DFE2
Pockets
7 · best druggability 0.80

Structure

1 distinct chain · 39% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALeucine--tRNA ligaseprotein85739% helix, 23% strandQ8DFE2

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
110140.800.8183empty
26080.740.8151empty
31040.480.8126empty
41130.440.7716empty
5660.410.8118empty

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