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AlphaFold monomer V2.0 prediction for leucine--tRNA ligase (Q8U2E6)

Analyse AlphaFold monomer V2.0 prediction for leucine--tRNA ligase (Q8U2E6) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q8U2E6
Type
protein
Length
967 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
Molecule
Leucine--tRNA ligase
UniProt
Q8U2E6
Pockets
7 · best druggability 0.77

Structure

1 distinct chain · 51% helix, 18% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALeucine--tRNA ligaseprotein96751% helix, 18% strandQ8U2E6

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111290.770.7980empty
24200.700.8135empty
3640.430.8214empty
41190.400.7521empty
5500.380.8120empty

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