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AlphaFold monomer V2.0 prediction for lysine--tRNA ligase (Q9RHV9)

Analyse AlphaFold monomer V2.0 prediction for lysine--tRNA ligase (Q9RHV9) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9RHV9
Type
protein
Length
494 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
Molecule
Lysine--tRNA ligase
UniProt
Q9RHV9
Pockets
4 · best druggability 0.74

Structure

1 distinct chain · 37% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALysine--tRNA ligaseprotein49437% helix, 25% strandQ9RHV9

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16330.740.8166empty
21050.350.7322empty
3670.290.7319empty
4670.270.7211empty

Compared structures

  • 3E9H · Lysyl-tRNA synthetase from bacillus stearothermophilus complexed with L-lysylsulfamoyl… · an experimental structure of the same protein · chain A against D, TM-score 0.97
  • 3E9H · Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with L-Lysylsulfamoyl… · an experimental structure of the same protein · chain A against D, TM-score 0.97
  • 3A74 · Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with Diadenosine… · an experimental structure of the same protein · chain A against D, TM-score 0.97
  • 3A74 · Lysyl-tRNA synthetase from bacillus stearothermophilus complexed with diadenosine… · an experimental structure of the same protein · chain A against D, TM-score 0.97
  • 3E9I · Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with L-Lysine… · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 3E9I · Lysyl-tRNA synthetase from bacillus stearothermophilus complexed with L-lysine… · an experimental structure of the same protein · chain A against A, TM-score 0.97

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