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AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (B8DPD6)

Analyse AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (B8DPD6) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
B8DPD6
Type
protein
Length
938 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x1D85cf76AA8a024dd37f8dd64B4eD5691Eb91E72
Molecule
Isoleucine--tRNA ligase
UniProt
B8DPD6
Pockets
6 · best druggability 0.74

Structure

1 distinct chain · 46% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AIsoleucine--tRNA ligaseprotein93846% helix, 19% strandB8DPD6

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16560.740.8061empty
26690.730.7949empty
32880.610.7937empty
41390.490.7922empty
51180.360.7322empty

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