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AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (Q9Z972)

Analyse AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (Q9Z972) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9Z972
Type
protein
Length
1,043 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x661f92Fc5950020C7aB410B5F5b9a3f429F49Ae5
Molecule
Isoleucine--tRNA ligase
UniProt
Q9Z972
Pockets
10 · best druggability 0.76

Structure

1 distinct chain · 45% helix, 22% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AIsoleucine--tRNA ligaseprotein104345% helix, 22% strandQ9Z972

Pockets

10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
112000.760.7891empty
26550.650.7546empty
34280.640.7832empty
41470.530.8125empty
51560.500.7820empty

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