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AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (C0ZG86)

Analyse AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (C0ZG86) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
C0ZG86
Type
protein
Length
925 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xC35EFAFBd6C1C86993de1c3D20c02e3f198163fB
Molecule
Isoleucine--tRNA ligase
UniProt
C0ZG86
Pockets
10 · best druggability 0.77

Structure

1 distinct chain · 45% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AIsoleucine--tRNA ligaseprotein92545% helix, 19% strandC0ZG86

Pockets

10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18420.770.8080empty
23960.640.7834empty
31410.610.8519empty
41560.520.8022empty
51410.460.7724empty

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