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AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (B7J0S6)

Analyse AlphaFold monomer V2.0 prediction for isoleucine--tRNA ligase (B7J0S6) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
B7J0S6
Type
protein
Length
1,042 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
Molecule
Isoleucine--tRNA ligase
UniProt
B7J0S6
Pockets
12 · best druggability 0.75

Structure

1 distinct chain · 47% helix, 22% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AIsoleucine--tRNA ligaseprotein104247% helix, 22% strandB7J0S6

Pockets

12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19640.750.7891empty
27670.670.7544empty
33780.610.7732empty
4870.580.8722empty
51570.480.7724empty

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