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AlphaFold monomer V2.0 prediction for metalloreductase STEAP4 (Q4V8K1)

Analyse AlphaFold monomer V2.0 prediction for metalloreductase STEAP4 (Q4V8K1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q4V8K1
Type: protein
Length: 470 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
Molecule: Metalloreductase STEAP4
UniProt: Q4V8K1
Pockets: 3 · best druggability 0.72

Structure

1 distinct chain · 60% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Metalloreductase STEAP4	protein	470	60% helix, 9% strand	Q4V8K1

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	476	0.72	0.81	43	empty
2	347	0.62	0.78	37	empty
3	75	0.33	0.75	15	empty

Compared structures

2YJZ · Rat STEAP4 oxidoreductase domain complexed with NADP · an experimental structure of the same protein · chain A against A, TM-score 0.37
2YJZ · Rat STEAP4 oxidoreductase domain complexed with NADP · an experimental structure of the same protein · chain A against A, TM-score 0.37

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4V8K1
Elsewhere: UniProt Q4V8K1 · AlphaFold DB Q4V8K1

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