Research workbench
AlphaFold monomer V2.0 prediction for protein STE5 (P32917)
Analyse AlphaFold monomer V2.0 prediction for protein STE5 (P32917) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P32917
- Type
- protein
- Length
- 917 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
- Molecule
- Protein STE5
- UniProt
- P32917
- Pockets
- 8 · best druggability 0.75
Structure
1 distinct chain · 18% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein STE5 | protein | 917 | 18% helix, 14% strand | P32917 |
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 688 | 0.75 | 0.81 | 53 | empty |
| 2 | 314 | 0.55 | 0.75 | 40 | empty |
| 3 | 221 | 0.46 | 0.73 | 31 | empty |
| 4 | 82 | 0.40 | 0.78 | 15 | empty |
| 5 | 64 | 0.34 | 0.76 | 15 | empty |
Compared structures
- 4F2H · Structure of the minimal STE5 vwa domain subject to autoinhibition by the STE5 pH domain · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 4F2H · Structure of the minimal Ste5 VWA domain subject to autoinhibition by the Ste5 PH domain · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 3FZE · Structure of the 'minimal scaffold' (ms) domain of Ste5 that cocatalyzes Fus3… · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 3FZE · Structure of the 'minimal scaffold' (ms) domain of STE5 that cocatalyzes FUS3… · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 2KGN · Solution structure of Ste5PM24 in the zwitterionic DPC micelle · an experimental structure of the same protein · chain A against A, TM-score 0.02
- 2KGN · Solution structure of STE5PM24 in the zwitterionic dpc micelle · an experimental structure of the same protein · chain A against A, TM-score 0.02
- 2L4U · Solution structure of Ste5PM24 in the presence of SDS micelle · an experimental structure of the same protein · chain A against A, TM-score 0.02
- 2L4U · Solution structure of STE5PM24 in the presence of sds micelle · an experimental structure of the same protein · chain A against A, TM-score 0.02
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32917
- Elsewhere: UniProt P32917 · AlphaFold DB P32917
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