Research workbench

AlphaFold monomer V2.0 prediction for ATP-dependent DNA helicase SRS2 (P12954)

Analyse AlphaFold monomer V2.0 prediction for ATP-dependent DNA helicase SRS2 (P12954) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: P12954
Type: protein
Length: 1,174 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x4c8Ed8aBe53FF28747ea8f51447F5Cfe355Ed923
Molecule: ATP-dependent DNA helicase SRS2
UniProt: P12954
Pockets: 11 · best druggability 0.81

Structure

1 distinct chain · 40% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ATP-dependent DNA helicase SRS2	protein	1174	40% helix, 8% strand	P12954

Pockets

11 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1106	0.81	0.82	100	empty
2	753	0.66	0.74	49	empty
3	341	0.59	0.76	40	empty
4	180	0.54	0.79	28	empty
5	180	0.53	0.79	27	empty

Compared structures

3V62 · Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to… · an experimental structure of the same protein · chain A against C, TM-score 0.01
3V62 · Structure of the S. cerevisiae SRS2 C-terminal domain in complex with PCNA conjugated to… · an experimental structure of the same protein · chain A against C, TM-score 0.01

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P12954
Elsewhere: UniProt P12954 · AlphaFold DB P12954

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