Research workbench

AlphaFold monomer V2.0 prediction for srsf protein kinase 2 (P78362)

Analyse AlphaFold monomer V2.0 prediction for srsf protein kinase 2 (P78362) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: P78362
Type: protein
Length: 688 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x29881a02D129107C6a36da89fe03D8284a85EFE1
Molecule: Srsf protein kinase 2
UniProt: P78362
Pockets: 5 · best druggability 0.85

Structure

1 distinct chain · 30% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Srsf protein kinase 2	protein	688	30% helix, 9% strand	P78362

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1038	0.85	0.85	93	empty
2	136	0.50	0.79	16	empty
3	106	0.41	0.76	22	empty
4	71	0.37	0.78	17	empty
5	63	0.31	0.75	15	empty

Compared structures

5MYV · Crystal structure of SRPK2 in complex with compound 1 · an experimental structure of the same protein · chain A against A, TM-score 0.50
5MYV · Crystal structure of SRPK2 in complex with compound 1 · an experimental structure of the same protein · chain A against A, TM-score 0.50
7ZKX · SRPK2 in complex with inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.49

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P78362
Elsewhere: UniProt P78362 · AlphaFold DB P78362

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