Research workbench
AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 1 (O77761)
Analyse AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 1 (O77761) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O77761
- Type
- protein
- Length
- 550 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
- Molecule
- Sterol O-acyltransferase 1
- UniProt
- O77761
- Pockets
- 8 · best druggability 0.86
Structure
1 distinct chain · 67% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sterol O-acyltransferase 1 | protein | 550 | 67% helix, 1% strand | O77761 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1048 | 0.86 | 0.87 | 86 | empty |
| 2 | 250 | 0.66 | 0.82 | 21 | empty |
| 3 | 139 | 0.59 | 0.84 | 20 | empty |
| 4 | 216 | 0.54 | 0.77 | 23 | empty |
| 5 | 54 | 0.48 | 0.86 | 23 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O77761
- Elsewhere: UniProt O77761 · AlphaFold DB O77761
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