Research workbench
AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 1 (O77760)
Analyse AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 1 (O77760) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O77760
- Type
- protein
- Length
- 550 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd91633319BDB0a92cbC4f08DeA734Bf74C030064
- Molecule
- Sterol O-acyltransferase 1
- UniProt
- O77760
- Pockets
- 7 · best druggability 0.86
Structure
1 distinct chain · 67% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sterol O-acyltransferase 1 | protein | 550 | 67% helix, 1% strand | O77760 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 967 | 0.86 | 0.87 | 83 | empty |
| 2 | 262 | 0.65 | 0.81 | 21 | empty |
| 3 | 119 | 0.54 | 0.83 | 21 | empty |
| 4 | 141 | 0.53 | 0.80 | 19 | empty |
| 5 | 81 | 0.44 | 0.80 | 23 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O77760
- Elsewhere: UniProt O77760 · AlphaFold DB O77760
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