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AlphaFold monomer V2.0 prediction for slit and ntrk-like protein 1 (Q96PX8)

Analyse AlphaFold monomer V2.0 prediction for slit and ntrk-like protein 1 (Q96PX8) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q96PX8
Type
protein
Length
696 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xf87a97E0A4bB354D834857B14296240B167cbe70
Molecule
Slit and ntrk-like protein 1
UniProt
Q96PX8
Pockets
3 · best druggability 0.71

Structure

1 distinct chain · 16% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASlit and ntrk-like protein 1protein69616% helix, 15% strandQ96PX8

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16090.710.7976empty
21220.690.9136empty
31770.430.7430empty

Modifications

Observed in the structure: 8 disulfide (disulfide).

Compared structures

  • 4RCA · Crystal structure of human PTPdelta and human Slitrk1 complex · an experimental structure of the same protein · chain A against B, TM-score 0.34
  • 4RCA · Crystal structure of human ptpdelta and human SLITRK1 complex · an experimental structure of the same protein · chain A against B, TM-score 0.34
  • 4RCW · Crystal structure of human Slitrk1 · an experimental structure of the same protein · chain A against A, TM-score 0.33
  • 4RCW · Crystal structure of human SLITRK1 · an experimental structure of the same protein · chain A against A, TM-score 0.33

Analyse

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