Research workbench
AlphaFold monomer V2.0 prediction for SH2B adapter protein 1 (Q91ZM2)
Analyse AlphaFold monomer V2.0 prediction for SH2B adapter protein 1 (Q91ZM2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q91ZM2
- Type
- protein
- Length
- 756 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
- Molecule
- SH2B adapter protein 1
- UniProt
- Q91ZM2
- Pockets
- 3 · best druggability 0.54
Structure
1 distinct chain · 15% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SH2B adapter protein 1 | protein | 756 | 15% helix, 11% strand | Q91ZM2 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 265 | 0.54 | 0.76 | 25 | empty |
| 2 | 243 | 0.46 | 0.72 | 26 | empty |
| 3 | 54 | 0.26 | 0.73 | 12 | empty |
Compared structures
- 8ATK · The SH2 domain of mouse SH2B1 · an experimental structure of the same protein · chain A against A, TM-score 0.14
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q91ZM2
- Elsewhere: UniProt Q91ZM2 · AlphaFold DB Q91ZM2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.