Research workbench
AlphaFold monomer V2.0 prediction for sphingosine-1-phosphate lyase 1 (Q8R0X7)
Analyse AlphaFold monomer V2.0 prediction for sphingosine-1-phosphate lyase 1 (Q8R0X7) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8R0X7
- Type
- protein
- Length
- 568 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x30b967CB2B3168F5Aa05Ec10C8CFFa3D82E84396
- Molecule
- Sphingosine-1-phosphate lyase 1
- UniProt
- Q8R0X7
- Pockets
- 6 · best druggability 0.62
Structure
1 distinct chain · 50% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sphingosine-1-phosphate lyase 1 | protein | 568 | 50% helix, 11% strand | Q8R0X7 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 504 | 0.62 | 0.75 | 70 | empty |
| 2 | 127 | 0.47 | 0.78 | 20 | empty |
| 3 | 51 | 0.42 | 0.83 | 17 | empty |
| 4 | 117 | 0.40 | 0.76 | 22 | empty |
| 5 | 60 | 0.31 | 0.76 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8R0X7
- Elsewhere: UniProt Q8R0X7 · AlphaFold DB Q8R0X7
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