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AlphaFold monomer V2.0 prediction for chromatin structure-remodeling complex subunit SFH1 (Q06168)

Analyse AlphaFold monomer V2.0 prediction for chromatin structure-remodeling complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q06168
Type
protein
Length
426 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x4d07E6a23DeB6B95bd9b90EcB67368b7e8D3B77e
Molecule
Chromatin structure-remodeling complex subunit SFH1
UniProt
Q06168
Pockets
4 · best druggability 0.71

Structure

1 distinct chain · 32% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AChromatin structure-remodeling complex subunit SFH1protein42632% helix, 11% strandQ06168

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18990.710.7672empty
23670.700.8333empty
32180.470.7424empty
4950.360.7517empty

Compared structures

  • 6V92 · RSC-NCP · an experimental structure of the same protein · chain A against Q, TM-score 0.45
  • 6V92 · RSC-NCP · an experimental structure of the same protein · chain A against Q, TM-score 0.45
  • 6V8O · RSC CORE · an experimental structure of the same protein · chain A against Q, TM-score 0.45
  • 6TDA · Structure of SWI/SNF chromatin remodeler rsc bound to a nucleosome · an experimental structure of the same protein · chain A against K, TM-score 0.43
  • 6K15 · RSC substrate-recruitment module · an experimental structure of the same protein · chain A against G, TM-score 0.43
  • 6K15 · Rsc substrate-recruitment module · an experimental structure of the same protein · chain A against G, TM-score 0.43
  • 6KW5 · The classc rsc-nucleosome complex · an experimental structure of the same protein · chain A against G, TM-score 0.43
  • 6KW4 · The classb rsc-nucleosome complex · an experimental structure of the same protein · chain A against G, TM-score 0.43
  • 6KW3 · The classa rsc-nucleosome complex · an experimental structure of the same protein · chain A against G, TM-score 0.42

Analyse

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