Research workbench
AlphaFold monomer V2.0 prediction for septin-9 (Q9UHD8)
Analyse AlphaFold monomer V2.0 prediction for septin-9 (Q9UHD8) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9UHD8
- Type
- protein
- Length
- 586 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbff27Dc0a932A6E0d9Fe883AAbD1BF27bB95A69F
- Molecule
- Septin-9
- UniProt
- Q9UHD8
- Pockets
- 4 · best druggability 0.76
Structure
1 distinct chain · 22% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Septin-9 | protein | 586 | 22% helix, 10% strand | Q9UHD8 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 906 | 0.76 | 0.79 | 56 | empty |
| 2 | 152 | 0.49 | 0.78 | 31 | empty |
| 3 | 99 | 0.44 | 0.79 | 16 | empty |
| 4 | 80 | 0.32 | 0.73 | 15 | empty |
Compared structures
- 5CYO · High resolution septin 9 GTPase domain in complex with GDP · an experimental structure of the same protein · chain A against A, TM-score 0.45
- 5CYO · High resolution Septin 9 GTPase domain in complex with GDP · an experimental structure of the same protein · chain A against A, TM-score 0.45
- 4YQF · GTPase domain of human septin 9 · an experimental structure of the same protein · chain A against A, TM-score 0.44
- 4YQF · GTPase domain of Human Septin 9 · an experimental structure of the same protein · chain A against A, TM-score 0.44
- 5CYP · GTPase domain of septin 9 in complex with GTP-gamma-S · an experimental structure of the same protein · chain A against A, TM-score 0.42
- 5CYP · GTPase domain of Septin 9 in complex with GTP-gamma-S · an experimental structure of the same protein · chain A against A, TM-score 0.42
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UHD8
- Elsewhere: UniProt Q9UHD8 · AlphaFold DB Q9UHD8
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