Research workbench

AlphaFold monomer V2.0 prediction for sterol carrier protein 2 (P22307)

Analyse AlphaFold monomer V2.0 prediction for sterol carrier protein 2 (P22307) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: P22307
Type: protein
Length: 547 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xEcFdC9Af6f95741e8FeAA0c9b6c43976C0126196
Molecule: Sterol carrier protein 2
UniProt: P22307
Pockets: 2 · best druggability 0.74

Structure

1 distinct chain · 42% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sterol carrier protein 2	protein	547	42% helix, 19% strand	P22307

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	583	0.74	0.81	55	empty
2	67	0.45	0.82	13	empty

Compared structures

2C0L · Tpr domain of human PEX5P in complex with human MSCP2 · an experimental structure of the same protein · chain A against B, TM-score 0.21
2C0L · Tpr domain of human PEX5P in complex with human MSCP2 · an experimental structure of the same protein · chain A against B, TM-score 0.21
1QND · Sterol carrier protein-2, NMR, 20 structures · an experimental structure of the same protein · chain A against A, TM-score 0.19
1QND · Sterol carrier protein-2, NMR, 20 structures · an experimental structure of the same protein · chain A against A, TM-score 0.19

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22307
Elsewhere: UniProt P22307 · AlphaFold DB P22307

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