Research workbench
AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit delta (O46547)
Analyse AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O46547
- Type
- protein
- Length
- 638 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xaa53776A41fB2e67da75A96E8a53746b6874aAB4
- Molecule
- Amiloride-sensitive sodium channel subunit delta
- UniProt
- O46547
- Pockets
- 8 · best druggability 0.79
Structure
1 distinct chain · 30% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Amiloride-sensitive sodium channel subunit delta | protein | 638 | 30% helix, 18% strand | O46547 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 629 | 0.79 | 0.84 | 81 | empty |
| 2 | 278 | 0.66 | 0.82 | 29 | empty |
| 3 | 186 | 0.53 | 0.78 | 35 | empty |
| 4 | 175 | 0.46 | 0.75 | 20 | empty |
| 5 | 90 | 0.34 | 0.74 | 24 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O46547
- Elsewhere: UniProt O46547 · AlphaFold DB O46547
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