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AlphaFold monomer V2.0 prediction for ganglioside GM2 activator (Q60648)

Analyse AlphaFold monomer V2.0 prediction for ganglioside GM2 activator (Q60648) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q60648
Type: protein
Length: 193 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x619F51Fb686eB178E60C23E8610260c3C69601D6
Molecule: Ganglioside GM2 activator
UniProt: Q60648
Pockets: 1 · best druggability 0.78

Structure

1 distinct chain · 10% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ganglioside GM2 activator	protein	193	10% helix, 45% strand	Q60648

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1039	0.78	0.79	68	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

2AGC · Crystal structure of mouse GM2- activator protein · an experimental structure of the same protein · chain A against A, TM-score 0.80
2AGC · Crystal Structure of mouse GM2- activator Protein · an experimental structure of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q60648
Elsewhere: UniProt Q60648 · AlphaFold DB Q60648

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