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AlphaFold monomer V2.0 prediction for holliday junction ATP-dependent DNA helicase ruva (Q9F1Q3)

Analyse AlphaFold monomer V2.0 prediction for holliday junction ATP-dependent DNA… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9F1Q3
Type
protein
Length
191 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xC29de81a61aaA258d315f09cc8A868dd942DA167
Molecule
Holliday junction ATP-dependent DNA helicase ruva
UniProt
Q9F1Q3
Pockets
2 · best druggability 0.45

Structure

1 distinct chain · 49% helix, 21% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHolliday junction ATP-dependent DNA helicase ruvaprotein19149% helix, 21% strandQ9F1Q3

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11510.450.7623empty
2670.330.7511empty

Compared structures

  • 1IXR · Ruva-ruvb complex · an experimental structure of the same protein · chain A against B, TM-score 0.71
  • 1IXR · RuvA-RuvB complex · an experimental structure of the same protein · chain A against B, TM-score 0.71
  • 8GH8 · RuvA Holliday junction DNA complex · an experimental structure of the same protein · chain A against B, TM-score 0.54
  • 1IXS · Structure of RuvB complexed with RuvA domain III · an experimental structure of the same protein · chain A against A, TM-score 0.26
  • 1IXS · Structure of ruvb complexed with ruva domain III · an experimental structure of the same protein · chain A against A, TM-score 0.26

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