Research workbench
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC7 (P17890)
Analyse AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P17890
- Type
- protein
- Length
- 251 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
- Molecule
- DNA-directed RNA polymerase III subunit RPC7
- UniProt
- P17890
- Pockets
- 4 · best druggability 0.55
Structure
1 distinct chain · 24% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase III subunit RPC7 | protein | 251 | 24% helix, 1% strand | P17890 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 229 | 0.55 | 0.78 | 20 | empty |
| 2 | 95 | 0.38 | 0.76 | 19 | empty |
| 3 | 80 | 0.36 | 0.76 | 14 | empty |
| 4 | 76 | 0.31 | 0.74 | 20 | empty |
Compared structures
- 7Z1N · Structure of yeast RNA Polymerase III Delta C53-C37-C11 · an experimental structure of the same protein · chain A against Q, TM-score 0.29
- 7Z1N · Structure of yeast RNA polymerase III delta C53-C37-C11 · an experimental structure of the same protein · chain A against Q, TM-score 0.29
- 7Z1M · Structure of yeast RNA Polymerase III Elongation Complex (EC) · an experimental structure of the same protein · chain A against Q, TM-score 0.29
- 7Z1O · Structure of yeast RNA Polymerase III PTC + NTPs · an experimental structure of the same protein · chain A against Q, TM-score 0.29
- 7Z2Z · Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A · an experimental structure of the same protein · chain A against Q, TM-score 0.29
- 7Z1L · Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC) · an experimental structure of the same protein · chain A against Q, TM-score 0.29
- 8BWS · Structure of yeast RNA Polymerase III elongation complex at 3.3 A · an experimental structure of the same protein · chain A against Q, TM-score 0.28
- 5FJ9 · Cryo-EM structure of yeast apo RNA polymerase III at 4.6 a · an experimental structure of the same protein · chain A against Q, TM-score 0.19
- 5FJ9 · Cryo-EM structure of yeast apo RNA polymerase III at 4.6 A · an experimental structure of the same protein · chain A against Q, TM-score 0.19
- 6TUT · Cryo-EM structure of the RNA polymerase III-MAF1 complex · an experimental structure of the same protein · chain A against Q, TM-score 0.19
- 6TUT · Cryo-EM structure of the RNA Polymerase III-Maf1 complex · an experimental structure of the same protein · chain A against Q, TM-score 0.19
- 6EU0 · RNA polymerase III open pre-initiation complex (oc-pic) · an experimental structure of the same protein · chain A against Q, TM-score 0.18
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17890
- Elsewhere: UniProt P17890 · AlphaFold DB P17890
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