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AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit RPC7 (P17890)

Analyse AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase III subunit… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P17890
Type
protein
Length
251 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
Molecule
DNA-directed RNA polymerase III subunit RPC7
UniProt
P17890
Pockets
4 · best druggability 0.55

Structure

1 distinct chain · 24% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA-directed RNA polymerase III subunit RPC7protein25124% helix, 1% strandP17890

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12290.550.7820empty
2950.380.7619empty
3800.360.7614empty
4760.310.7420empty

Compared structures

  • 7Z1N · Structure of yeast RNA Polymerase III Delta C53-C37-C11 · an experimental structure of the same protein · chain A against Q, TM-score 0.29
  • 7Z1N · Structure of yeast RNA polymerase III delta C53-C37-C11 · an experimental structure of the same protein · chain A against Q, TM-score 0.29
  • 7Z1M · Structure of yeast RNA Polymerase III Elongation Complex (EC) · an experimental structure of the same protein · chain A against Q, TM-score 0.29
  • 7Z1O · Structure of yeast RNA Polymerase III PTC + NTPs · an experimental structure of the same protein · chain A against Q, TM-score 0.29
  • 7Z2Z · Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A · an experimental structure of the same protein · chain A against Q, TM-score 0.29
  • 7Z1L · Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC) · an experimental structure of the same protein · chain A against Q, TM-score 0.29
  • 8BWS · Structure of yeast RNA Polymerase III elongation complex at 3.3 A · an experimental structure of the same protein · chain A against Q, TM-score 0.28
  • 5FJ9 · Cryo-EM structure of yeast apo RNA polymerase III at 4.6 a · an experimental structure of the same protein · chain A against Q, TM-score 0.19
  • 5FJ9 · Cryo-EM structure of yeast apo RNA polymerase III at 4.6 A · an experimental structure of the same protein · chain A against Q, TM-score 0.19
  • 6TUT · Cryo-EM structure of the RNA polymerase III-MAF1 complex · an experimental structure of the same protein · chain A against Q, TM-score 0.19
  • 6TUT · Cryo-EM structure of the RNA Polymerase III-Maf1 complex · an experimental structure of the same protein · chain A against Q, TM-score 0.19
  • 6EU0 · RNA polymerase III open pre-initiation complex (oc-pic) · an experimental structure of the same protein · chain A against Q, TM-score 0.18

Analyse

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