Research workbench
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA49 (Q6GLI9)
Analyse AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q6GLI9
- Type
- protein
- Length
- 419 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd91633319BDB0a92cbC4f08DeA734Bf74C030064
- Molecule
- DNA-directed RNA polymerase I subunit RPA49
- UniProt
- Q6GLI9
- Pockets
- 4 · best druggability 0.60
Structure
1 distinct chain · 45% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase I subunit RPA49 | protein | 419 | 45% helix, 19% strand | Q6GLI9 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 352 | 0.60 | 0.77 | 45 | empty |
| 2 | 139 | 0.51 | 0.79 | 24 | empty |
| 3 | 149 | 0.45 | 0.76 | 27 | empty |
| 4 | 63 | 0.28 | 0.73 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6GLI9
- Elsewhere: UniProt Q6GLI9 · AlphaFold DB Q6GLI9
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