Research workbench
AlphaFold monomer V2.0 prediction for glucose-1-phosphate thymidylyltransferase 1 (P37744)
Analyse AlphaFold monomer V2.0 prediction for glucose-1-phosphate thymidylyltransferase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P37744
- Type
- protein
- Length
- 293 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x79a905d858Ce72991FD6E7a9C6498620f42E146D
- Molecule
- Glucose-1-phosphate thymidylyltransferase 1
- UniProt
- P37744
- Pockets
- 4 · best druggability 0.69
Structure
1 distinct chain · 38% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glucose-1-phosphate thymidylyltransferase 1 | protein | 293 | 38% helix, 24% strand | P37744 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 356 | 0.69 | 0.82 | 37 | empty |
| 2 | 212 | 0.53 | 0.77 | 21 | empty |
| 3 | 74 | 0.32 | 0.75 | 14 | empty |
| 4 | 54 | 0.28 | 0.74 | 12 | empty |
Compared structures
- 1H5S · Thymidylyltransferase complexed with TMP · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 1H5S · Thymidylyltransferase complexed with tmp · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 1H5T · Thymidylyltransferase complexed with thymidylyldiphosphate-glucose · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 1H5T · Thymidylyltransferase complexed with Thymidylyldiphosphate-glucose · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 1H5R · Thymidylyltransferase complexed with thimidine and glucose-1-phospate · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 1H5R · Thymidylyltransferase complexed with Thimidine and Glucose-1-phospate · an experimental structure of the same protein · chain A against B, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37744
- Elsewhere: UniProt P37744 · AlphaFold DB P37744
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