AlphaFold monomer V2.0 prediction for 60S ribosomal protein L7A (P62424)

Structure

1 distinct chain · 46% helix, 7% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 8XSX · Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 · an experimental structure of the same protein · chain A against LG, TM-score 0.88
• 8OHD · 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) · an experimental structure of the same protein · chain A against LG, TM-score 0.88
• 6ZMI · SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex · an experimental structure of the same protein · chain A against LG, TM-score 0.88
• 6ZMO · SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex · an experimental structure of the same protein · chain A against LG, TM-score 0.88
• 8OJ5 · 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution) · an experimental structure of the same protein · chain A against LG, TM-score 0.88
• 6ZM7 · SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex · an experimental structure of the same protein · chain A against LG, TM-score 0.88
• 8OJ8 · 60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) · an experimental structure of the same protein · chain A against LG, TM-score 0.88
• 6ZME · SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex · an experimental structure of the same protein · chain A against LG, TM-score 0.88
• 8OJ0 · 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) · an experimental structure of the same protein · chain A against LG, TM-score 0.88
• 8GLP · mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus… · an experimental structure of the same protein · chain A against LG, TM-score 0.87
• 6Z6M · Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 · an experimental structure of the same protein · chain A against LG, TM-score 0.87
• 8IFD · Dibekacin-added human 80S ribosome · an experimental structure of the same protein · chain A against 2B, TM-score 0.87

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P62424
• Elsewhere: UniProt P62424 · AlphaFold DB P62424