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AlphaFold monomer V2.0 prediction for 50S ribosomal protein L2 (B7MCT2)

Analyse AlphaFold monomer V2.0 prediction for 50S ribosomal protein L2 (B7MCT2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
B7MCT2
Type
protein
Length
273 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xbff27Dc0a932A6E0d9Fe883AAbD1BF27bB95A69F
Molecule
50S ribosomal protein L2
UniProt
B7MCT2
Pockets
4 · best druggability 0.50

Structure

1 distinct chain · 11% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A50S ribosomal protein L2protein27311% helix, 30% strandB7MCT2

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12290.500.7534empty
2680.390.7919empty
3620.340.7610empty
4520.230.7216empty

Compared structures

  • 5WFS · 70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4) · an experimental structure of the same protein · chain A against C, TM-score 0.99
  • 6C4I · Conformation of methylated GGQ in the peptidyl transferase center during translation… · an experimental structure of the same protein · chain A against C, TM-score 0.99
  • 5WF0 · 70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2) · an experimental structure of the same protein · chain A against C, TM-score 0.99
  • 6DNC · E.coli RF1 bound to E.coli 70S ribosome in response to UAU sense A-site codon · an experimental structure of the same protein · chain A against F, TM-score 0.98

Analyse

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