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AlphaFold monomer V2.0 prediction for pre-rRNA-processing protein RIX1 (P38883)

Analyse AlphaFold monomer V2.0 prediction for pre-rRNA-processing protein RIX1 (P38883) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P38883
Type
protein
Length
763 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x8719F119347D3c1a2ffc2ea3A2408f52f4c89F2A
Molecule
Pre-rRNA-processing protein RIX1
UniProt
P38883
Pockets
5 · best druggability 0.65

Structure

1 distinct chain · 58% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APre-rRNA-processing protein RIX1protein76358% helix, 1% strandP38883

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13510.650.8038empty
21530.570.8221empty
32400.510.7633empty
4520.290.7513empty
5560.280.7413empty

Compared structures

  • 6YLE · RIX1-REA1 pre-60S particle - RIX1-subcomplex, body 3 (rigid body refinement) · an experimental structure of the same protein · chain A against C, TM-score 0.70
  • 6YLE · Rix1-Rea1 pre-60S particle - Rix1-subcomplex, body 3 (rigid body refinement) · an experimental structure of the same protein · chain A against C, TM-score 0.70
  • 6YLH · Rix1-Rea1 pre-60S particle - full composite structure · an experimental structure of the same protein · chain A against 6, TM-score 0.70

Analyse

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