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AlphaFold monomer V2.0 prediction for GTP cyclohydrolase-2 (Q8D2J0)

Analyse AlphaFold monomer V2.0 prediction for GTP cyclohydrolase-2 (Q8D2J0) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q8D2J0
Type
protein
Length
197 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
Molecule
GTP cyclohydrolase-2
UniProt
Q8D2J0
Pockets
2 · best druggability 0.75

Structure

1 distinct chain · 34% helix, 26% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGTP cyclohydrolase-2protein19734% helix, 26% strandQ8D2J0

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12540.750.8945empty
2580.290.7318empty

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