Research workbench
AlphaFold monomer V2.0 prediction for GTP cyclohydrolase-2 (P44571)
Analyse AlphaFold monomer V2.0 prediction for GTP cyclohydrolase-2 (P44571) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P44571
- Type
- protein
- Length
- 216 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC6F27A824B664EFA5726f983121805502318e85b
- Molecule
- GTP cyclohydrolase-2
- UniProt
- P44571
- Pockets
- 2 · best druggability 0.77
Structure
1 distinct chain · 33% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GTP cyclohydrolase-2 | protein | 216 | 33% helix, 22% strand | P44571 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 375 | 0.77 | 0.87 | 49 | empty |
| 2 | 102 | 0.38 | 0.74 | 21 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P44571
- Elsewhere: UniProt P44571 · AlphaFold DB P44571
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