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AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 10 (A1A4S6)

Analyse AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 10 (A1A4S6) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: A1A4S6
Type: protein
Length: 786 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
Molecule: Rho GTPase-activating protein 10
UniProt: A1A4S6
Pockets: 8 · best druggability 0.60

Structure

1 distinct chain · 47% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rho GTPase-activating protein 10	protein	786	47% helix, 10% strand	A1A4S6

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	417	0.60	0.76	37	empty
2	219	0.51	0.76	21	empty
3	132	0.42	0.76	21	empty
4	158	0.41	0.73	17	empty
5	146	0.41	0.74	22	empty

Compared structures

2MIO · Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo… · an experimental structure of the same protein · chain A against A, TM-score 0.07
2MIO · Solution NMR structure of SH3 domain 1 of rho GTPase-activating protein 10 from homo… · an experimental structure of the same protein · chain A against A, TM-score 0.07

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A1A4S6
Elsewhere: UniProt A1A4S6 · AlphaFold DB A1A4S6

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