Research workbench
AlphaFold monomer V2.0 prediction for RAS-specific guanine nucleotide-releasing factor 2 (P70392)
Analyse AlphaFold monomer V2.0 prediction for RAS-specific guanine nucleotide-releasing… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P70392
- Type
- protein
- Length
- 1,189 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4ED13986579E8e227b3ED6c02276c648754EC27
- Molecule
- RAS-specific guanine nucleotide-releasing factor 2
- UniProt
- P70392
- Pockets
- 8 · best druggability 0.84
Structure
1 distinct chain · 55% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAS-specific guanine nucleotide-releasing factor 2 | protein | 1189 | 55% helix, 9% strand | P70392 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1115 | 0.84 | 0.85 | 103 | empty |
| 2 | 636 | 0.79 | 0.84 | 56 | empty |
| 3 | 964 | 0.76 | 0.79 | 76 | empty |
| 4 | 112 | 0.53 | 0.82 | 20 | empty |
| 5 | 207 | 0.48 | 0.75 | 27 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P70392
- Elsewhere: UniProt P70392 · AlphaFold DB P70392
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